Human Anti-BRD7 Recombinant Antibody (clone D393)

Name: Human Anti-BRD7 Recombinant Antibody (clone D393)
SKU: DrMAB-259
Rating: 5 (1 reviews)

CAT#: DrMAB-259

Recombinant Human Antibody binds selectively to Human BRD7.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42389/1617_G10_2_selected.jpg

Subcellular Location and Protein Expression Figure 2 IF staining of human cell line Hep G2

Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60171/1327_A12_2_selected.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line CACO-2

Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42389/1721_G10_23_cr57eaab810c0ed_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/104091_B_9_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/103770_A_7_3.jpg

Normal Tissue Figure 6 Liver

Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/103770_A_7_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/103770_A_9_5.jpg

Normal Tissue Figure 8 Testis

Leydig cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Round or early spermatids
Staining:High
Intensity: Strong
Quantity: 75%-25%
Sertoli cells
Staining:High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining:High
Intensity: Strong
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/103770_A_5_6.jpg

Normal Tissue Figure 9 Lymph node

Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46458/103770_A_8_8.jpg

RNA Expression Figure 10 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166164-BRD7

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Type
Human IgG1

Specificity
Reacts with human BRD7

Species Reactivity
Human

Clone
D393

Applications
ELISA, IP-MS

Product Property

Purity
>95% as determined by analysis by SDS-PAGE

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
BRD7; bromodomain containing 7; BP75; NAG4; CELTIX1; bromodomain-containing protein 7; 75 kDa bromodomain protein; protein CELTIX-1

Gene ID
29117

UniProt ID
Q9NPI1

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - DrMAB-259.pdf

MSDS

MSDS - DrMAB-259.pdf

COA

Certificate of Analysis Lookup

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CAT	Product Name	Application	Type
VS-0325-XY262	Anti-BRD7 Immunohistochemistry Kit	IHC

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