Src homology domain 2 (SH2) scaffold protein anti-Phosphotyrosine (pY) (CAT#: SSW-L191)
The Src homology domain 2 (SH2) that bound phosphotyrosine (pY) was isolated from the library using Filter screening techonology. After affinity maturation, SH2 variants were identified having affinities (KD=1 nM) for phosphotyrosine (pY) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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Specifications
- Scaffold Name
- Src homology domain 2 (SH2)
- Origin
- PLCgamma C-terminal SH2 domain
- Core Structure
- α/β (~100)
- Variable Regions
- 5 aa
- Target
- Phosphotyrosine (pY)
- Expression Host
- E. coli
- Affinity Constant
- 1 nM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- PLCgamma C-terminal SH2 domain; Src homology domain 2 (SH2); phosphotyrosine; pY
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Rabbit Monoclonal Antibody Products
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2696 | Hi-Affi™ Recombinant Rabbit Anti-Phosphotyrosine Monoclonal Antibody (DS2696AB) | WB, IP, ICC, IHC, FC, ELISA | IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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