Src homology domain 2 (SH2) scaffold protein anti-Phosphotyrosine (pY)
CAT#: SSW-L191
The Src homology domain 2 (SH2) that bound phosphotyrosine (pY) was isolated from the library using Filter screening techonology. After affinity maturation, SH2 variants were identified having affinities (KD=1 nM) for phosphotyrosine (pY) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- Src homology domain 2 (SH2)
- Origin
- PLCgamma C-terminal SH2 domain
- Core Structure
- α/β (~100)
- Variable Regions
- 5 aa
- Target
- Phosphotyrosine (pY)
- Expression Host
- E. coli
- Affinity Constant
- 1 nM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- PLCgamma C-terminal SH2 domain; Src homology domain 2 (SH2); phosphotyrosine; pY
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