AbPlus™ Anti-ACY1 Magnetic Beads (VS-0724-YC960)
CAT#: VS-0724-YC960
The AbPlus Anti-ACY1 Magnetic Beads (VS-0724-YC960) is an innovative affinity resin which is bound with anti-ACY1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ACY1 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in renal tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36174/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in subsets of renal tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36175/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes -
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36174/98823_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36174/98823_A_7_4.jpg
Normal Tissue
Figure 5 High expression in kidney.
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36174/98823_A_8_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000243989-ACY1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-ACY1 specific antibody
- Target
- ACY1
- Immunogen
- Recombinant human ACY1, aa 1-408.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Nov 2010]
- Alternative Names
- Aminoacylase 1; N-Acyl-L-Amino-Acid Amidohydrolase; EC 3.5.1.14; ACY-1; Epididymis Secretory Protein Li 5; Aminoacylase-1;
- Gene ID
- 95
- UniProt ID
- Q03154
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACY1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3391z | Mouse Anti-ACY1 Recombinant Antibody (clone 20G5) | ELISA, IF, IHC, IP, WB | Mouse IgG1, κ |
| MOB-0612MZ | Mouse Anti-ACY1 Recombinant Antibody (clone 4F1-B7) | IF, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0020MZ | Chicken Anti-ACY1 (ab1) Polyclonal IgY | WB | Chicken antibody |
| BRD-0021MZ | Chicken Anti-ACY1 (ab2) Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0066 | Hi-Affi™ Rabbit Anti-ACY1 Recombinant Antibody (clone DS66AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1000 | AbPlus™ Anti-Acy1 Magnetic Beads (VS-0724-YC1000) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY38 | Anti-ACY1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY143 | Anti-Mouse ACY1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY142 | Anti-Human ACY1 Immunohistochemistry Kit | IHC |
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