DrugMonitor™ Anti-Alefacept Antibody (VS-1224-YC48) (CAT#: VS-1224-YC48)

Alefacept is an immunosuppressive dimeric fusion protein comprising the extracellular CD2-binding domain of human LFA-3 linked to the IgG1 Fc region, formerly used to treat moderate to severe chronic plaque psoriasis. The DrugMonitor™ Anti-Alefacept Antibody (VS-1224-YC48) is an anti-drug antibody (ADA) against Alefacept. This drug-based antibody is raised in mice immunized with the Alefacept. The anti-Alefacept antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Alefacept in samples.

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  • Datasheet
  • MSDS
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Specifications

  • Host Animal
  • Mouse
  • Specificity
  • Alefacept
  • Target
  • Alefacept
  • Immunogen
  • Alefacept
  • Type
  • Mouse IgG
  • Species Reactivity
  • Human
  • Purity
  • >95%
  • Purification
  • Protein G
  • Applications
  • ELISA, PK/PD, ADA control
  • Format
  • Liquid
  • Concentration
  • Batch-dependent
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
  • Generic name
  • Alefacept
  • Drug Weight
  • 51801.1 Da
  • Formula
  • C₂₃₀₆H₃₅₉₄N₆₁₀O₆₉₄S₂₆
  • Related Disease
  • Moderate to severe chronic plaque psoriasis

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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