AbPlus™ Anti-CRKL Magnetic Beads (VS-0724-YC365)
CAT#: VS-0724-YC365
The AbPlus Anti-CRKL Magnetic Beads (VS-0724-YC365) is an innovative affinity resin which is bound with anti-CRKL specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CRKL protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human fallopian tube
Immunohistochemical staining of human fallopian tube shows membranous and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1100/2588_A_7_7_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1100/2588_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1100/2588_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1100/2588_A_9_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1100/2588_A_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (K-562)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000099942-CRKL
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CRKL specific antibody
- Target
- CRKL
- Immunogen
- Recombinant human CRKL fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CRKL (CRK Like Proto-Oncogene, Adaptor Protein) is a Protein Coding gene. Diseases associated with CRKL include Chromosome 22Q11.2 Deletion Syndrome, Distal and Leukemia, Chronic Myeloid. Among its related pathways are RET signaling and Chronic myeloid leukemia. Gene Ontology (GO) annotations related to this gene include SH3/SH2 adaptor activity. An important paralog of this gene is CRK.
- Alternative Names
- CRK Like Proto-Oncogene, Adaptor Protein; V-Crk Avian Sarcoma Virus CT10 Oncogene Homolog-Like;
- Gene ID
- 1399
- UniProt ID
- P46109
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CRKL"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0808 | Hi-Affi™ Rabbit Anti-CRKL Recombinant Antibody (clone DS808AB) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX277 | Mouse Anti-CRKL Recombinant Antibody (clone 5E12) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS7-HM772 | Mouse Anti-CRKL Recombinant Antibody (clone CBL175HM) | WB, FCM, ELISA | Mouse IgG |
| VS13-YC247 | Rabbit Anti-CRKL Recombinant Antibody (VS13-YC247) | WB, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1675 | Anti-CRKL Immunohistochemistry Kit | IHC | |
| VS-0525-XY1676 | Anti-Mouse CRKL Immunohistochemistry Kit | IHC |
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