AbPlus™ Anti-DIABLO Magnetic Beads (VS-0724-YC676) (CAT#: VS-0724-YC676)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-DIABLO specific antibody

• Target
• DIABLO

• Immunogen
• Recombinant human SMAC/Diablo, aa 56-239.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

• Alternative Names
• Diablo IAP-Binding Mitochondrial Protein; Second Mitochondria-Derived Activator Of Caspase; Direct IAP-Binding Protein With Low PI; SMAC; Diablo, IAP-Binding Mitochondrial Protein; Diablo Homolog, Mitochondrial; Diablo-Like Protein; DFNA64;

• Gene ID
• 56616

• UniProt ID
• Q9NR28

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