DrugMonitor™ Rabbit Anti-Diphenhydramine Polyclonal Antibody (VS-0125-YC2192) (CAT#: VS-0125-YC2192)

Diphenhydramine, a first-generation H₁-antihistamine, provides antihistaminic and sedative effects, achieved through histamine receptor antagonism. It also exhibits marked anticholinergic properties. This product is the DrugMonitor™ Anti-Diphenhydramine Polyclonal Antibody (VS-0125-YC2192), specifically designed as an anti-drug antibody (ADA) that targets Diphenhydramine. The ADA was raised in rabbits immunized with Diphenhydramine and is suitable for use in ELISA and lateral flow assays. This antibody may be employed in pharmacokinetics (PK) and pharmacodynamics (PD) analyses, or as a reference standard in ADA assays. Furthermore, as a drug-based antibody, it serves as an exemplary tool for therapeutic drug monitoring, facilitating the determination of Diphenhydramine drug concentrations in various samples.