AbPlus™ Anti-DR1 Magnetic Beads (VS-0724-YC497) (CAT#: VS-0724-YC497)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-DR1 specific antibody

• Target
• DR1

• Immunogen
• Recombinant human DR1 fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]

• Alternative Names
• Down-Regulator Of Transcription 1; TATA-Binding Protein-Associated Phosphoprotein; Negative Cofactor 2-Beta; Negative Cofactor 2; NC2-BETA; Down-Regulator Of Transcription 1, TBP-Binding (Negative Cofactor 2);

• Gene ID
• 1810

• UniProt ID
• Q01658

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