Recombinant Anti-E. coli LacY Biparatopic Antibody, Tandem scFv (Clone nb 9309 x Clone 9047) (CAT#: VS-0525-YC58)

• Host Animal 1
• Camelid

• Host Animal 2
• Camelid

• Specificity
• E. coli LacY

• Species Reactivity
• E. coli

• Type
• Tandem sdAb

• Valency
• 1 + 1

• Clone 1
• nb 9309

• Clone 2
• 9047

• Epitope 1
• In LacYww includes residues from TM7 (Asn245 and Thr248), loop 7-8 (Phe251 and Ala252), TM8 (Gly254), loop 9-10 (Thr310), TM11 (Glu374), and also TM2 (Lys42).

• Epitope 2
• The periplasmic face of LacY

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Escherichia coli Lactose permease

• Introduction
• LacY is responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta, D-galactopyranoside (TMG), but not sucrose or fructose. The substrate specificity is directed toward the galactopyranosyl moiety of the substrate.

• Alternative Names
• LacY

• Gene ID
• 49585846

• UniProt ID
• P02920

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