Human Anti-EDN2 Recombinant Antibody (clone H10); Fab Fragment (CAT#: HPAB-0157CQ-F(E))
This product is a recombinant human antibody Fab fragment that recognizes EDN2. The antibody can bind to ET2 and inhibit ET2 with high affinity and selectivity. The ET2 binding proteins can be used to treat a variety of disorders, including angiogenesis-associated disorders.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/if_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/ihc_selected.jpg
Figure 3 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/60383_A_8_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/60383_A_8_3.jpg
Figure 4 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/60383_A_6_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28459/60383_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (CAPAN-2, EFO-21, HeLa, SCLC-21H, SK-BR-3, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000127129-EDN2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000127129-EDN2
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human Fab
- Specificity
- Human EDN2
- Species Reactivity
- Human
- Clone
- H10
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone H10"
See other products for "EDN2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0659CT | Recombinant Mouse anti-Human EDN2 Monoclonal antibody (EML287) | WB | |
| HPAB-0157CQ | Human Anti-EDN2 Recombinant Antibody (clone H10) | ELISA | Human IgG |
| HPAB-0158CQ | Human Anti-EDN2 Recombinant Antibody (clone F8) | ELISA | Human IgG |
| HPAB-0159CQ | Human Anti-EDN2 Recombinant Antibody (clone D5) | ELISA | Human IgG |
| HPAB-0160CQ | Human Anti-EDN2 Recombinant Antibody (clone C9) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0158CQ-F(E) | Human Anti-EDN2 Recombinant Antibody (clone F8); Fab Fragment | ELISA | Human Fab |
| HPAB-0159CQ-F(E) | Human Anti-EDN2 Recombinant Antibody (clone D5); Fab Fragment | ELISA | Human Fab |
| HPAB-0160CQ-F(E) | Human Anti-EDN2 Recombinant Antibody (clone C9); Fab Fragment | ELISA | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157CQ-S(P) | Human Anti-EDN2 Recombinant Antibody (clone H10); scFv Fragment | ELISA | Human scFv |
| HPAB-0158CQ-S(P) | Human Anti-EDN2 Recombinant Antibody (clone F8); scFv Fragment | ELISA | Human scFv |
| HPAB-0159CQ-S(P) | Human Anti-EDN2 Recombinant Antibody (clone D5); scFv Fragment | ELISA | Human scFv |
| HPAB-0160CQ-S(P) | Human Anti-EDN2 Recombinant Antibody (clone C9); scFv Fragment | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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