Mouse Anti-Mycobacterium tuberculosis CFP-10 Antibody (VS-0925-XY38)

CAT#: VS-0925-XY38

Mycobacterium tuberculosis CFP-10 antibodies target this secreted virulence protein, supporting ELISA for infection detection, immunoprecipitation to study ESAT-6/CFP-10 complexes, and research on its role in macrophage invasion. Key for tuberculosis diagnostic and virulence mechanism studies.

Specifications

  • Host Animal
  • Mouse
  • Applications
  • ELISA
  • Specificity
  • Mycobacterium tuberculosis CFP-10
  • Target
  • Mycobacterium tuberculosis CFP-10
  • Species Reactivity
  • Bacteria
  • Type
  • Mouse IgG2b
  • Purification
  • Protein A Purified
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.2
  • Preservative
  • 0.1% sodium azide
  • Storage
  • This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.

Target

  • Introduction
  • Mycobacterium tuberculosis CFP-10 (Culture Filtrate Protein 10) is a small secreted protein of Mycobacterium tuberculosis, often studied alongside its interacting partner ESAT-6 (Early Secreted Antigenic Target 6). It is encoded by genes within the RD1 (Region of Difference 1) locus-a genetic region critical for bacterial virulence. CFP-10 plays a role in bacterial invasion of host cells, particularly macrophages, and helps the bacterium establish intracellular infection. It has strong immunogenicity, specifically stimulating cell-mediated immunity, such as the activation of memory T cells. This property makes CFP-10 a key component in tuberculosis diagnostic tests (e.g., interferon-gamma release assays), as it can distinguish between latent and active infections. It is also a promising candidate for tuberculosis vaccines, as targeting CFP-10 may inhibit bacterial virulence and enhance host clearance of the pathogen.
  • Alternative Names
  • M. tuberculosis Culture Filtrate Protein 10, Mtb CFP-10
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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