Rabbit Anti-Mycobacterium tuberculosis GlcB Antibody (VS-0925-XY40)

CAT#: VS-0925-XY40

Mycobacterium tuberculosis GlcB antibodies recognize this metabolic enzyme, enabling Western blotting for expression analysis, ELISA for detection, and studies on its role in bacterial glycolysis and energy production. Useful for researching Mycobacterium tuberculosis survival in nutrient-limited host environments.

Specifications

  • Host Animal
  • Rabbit
  • Applications
  • WB, ELISA
  • Specificity
  • Mycobacterium tuberculosis GlcB
  • Target
  • Mycobacterium tuberculosis GlcB
  • Species Reactivity
  • Bacteria
  • Type
  • Rabbit IgG
  • Purification
  • Affinity chromatography Purified
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 15 mM sodium azide
  • Storage
  • This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.

Target

  • Introduction
  • Mycobacterium tuberculosis GlcB (Glyceraldehyde-3-Phosphate Dehydrogenase-like Protein, also known as Gap) is a metabolic enzyme and antigenic protein of Mycobacterium tuberculosis. Primarily, it functions in the bacterial glycolytic pathway, catalyzing the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate-an essential step for energy production and nutrient metabolism, supporting bacterial survival in nutrient-limited host environments (e.g., within macrophages). Beyond its metabolic role, GlcB exhibits immunogenicity, triggering both humoral and cellular immune responses in the host. It is a potential diagnostic marker for tuberculosis, as the presence of GlcB-specific antibodies or T-cell responses can indicate infection. Additionally, its conservation across Mycobacterium tuberculosis strains and role in critical metabolism make it a candidate for anti-tuberculosis drugs, as inhibiting GlcB may disrupt bacterial energy production and limit pathogenicity.
  • Alternative Names
  • M. tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase-like Protein, Mtb GlcB
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