Rabbit Anti-Mycobacterium tuberculosis MPT63 Antibody (VS-0925-XY43)
CAT#: VS-0925-XY43
Mycobacterium tuberculosis MPT63 antibodies bind this secreted protein, enabling Western blotting, ELISA for detection, and studies on its role in iron acquisition. Valuable for researching Mycobacterium tuberculosis nutrient uptake and virulence in iron-poor host tissues.
Specifications
- Host Animal
- Rabbit
- Applications
- WB
- Specificity
- Mycobacterium tuberculosis MPT63
- Target
- Mycobacterium tuberculosis MPT63
- Immunogen
- Recombinant Mycobacterium tuberculosis Immunogenic protein MPT63 protein
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Protein G Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 50% glycerol
- Preservative
- 0.03% ProClin 300
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Mycobacterium tuberculosis MPT63 (Mycobacterial Protein Target 63) is a small secreted protein of Mycobacterium tuberculosis, characterized by its high conservation across Mycobacterial species. Its exact biological function is still under investigation, but preliminary studies suggest it may be involved in bacterial iron acquisition-a critical process for Mycobacterium tuberculosis, as iron is scarce in the host. By facilitating iron uptake, MPT63 may support bacterial growth and survival during infection. MPT63 also exhibits immunogenicity, stimulating the host's immune system to produce specific antibodies and T-cell responses. This property makes it a potential diagnostic marker for tuberculosis, as MPT63-specific immune responses can be detected in infected individuals. Additionally, its conservation and potential role in virulence make it a candidate antigen for tuberculosis vaccines, with the goal of inhibiting bacterial iron metabolism and enhancing host clearance.
- Alternative Names
- M. tuberculosis Mycobacterial Protein Target 63, Mtb MPT63
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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