Rabbit Anti-Mycobacterium tuberculosis Tb10.3 Antibody (VS-0925-XY46)
CAT#: VS-0925-XY46
Mycobacterium tuberculosis Tb10.3 antibodies recognize this RD1-locus protein, enabling Western blotting, immunofluorescence, and studies on its role in bacterial secretion and host cell interaction. Useful for researching Mycobacterium tuberculosis virulence and immune evasion.
Specifications
- Host Animal
- Rabbit
- Applications
- WB, ELISA
- Specificity
- Mycobacterium tuberculosis Tb10.3
- Target
- Mycobacterium tuberculosis Tb10.3
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Affinity chromatography Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- 15 mM sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Mycobacterium tuberculosis Tb10.3 is a small, conserved protein of Mycobacterium tuberculosis, encoded by a gene within the RD1 locus-a region linked to bacterial virulence. It is often associated with ESAT-6 and CFP-10, though its exact functional role is less well-defined than these two proteins. Studies suggest Tb10.3 may be involved in bacterial secretion systems or host cell interaction, potentially aiding in bacterial invasion or intracellular survival. It exhibits immunogenicity, particularly stimulating cell-mediated immunity, such as the activation of T cells that recognize infected cells. This property makes Tb10.3 a potential candidate for tuberculosis vaccines, as it may enhance the host's ability to target virulent Mycobacterium tuberculosis strains. It also has potential as a diagnostic marker, though its use is less widespread than ESAT-6 or CFP-10, with ongoing research to evaluate its clinical utility.
- Alternative Names
- M. tuberculosis Tuberculosis Protein 10.3, Mtb Tb10.3
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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