Rabbit Anti-Mycobacterium tuberculosis Tb7.7 Antibody (VS-0925-XY48)
CAT#: VS-0925-XY48
Mycobacterium tuberculosis Tb7.7 antibodies target this RD1-encoded protein, facilitating Western blotting, immunoprecipitation, and studies on its role in intracellular survival. Valuable for researching Mycobacterium tuberculosis persistence in host macrophages.
Specifications
- Host Animal
- Rabbit
- Applications
- WB, ELISA
- Specificity
- Mycobacterium tuberculosis Tb7.7
- Target
- Mycobacterium tuberculosis Tb7.7
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Affinity chromatography Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- 15 mM sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Mycobacterium tuberculosis Tb7.7 is a small, conserved protein of Mycobacterium tuberculosis, with a role in bacterial virulence and host interaction. It is encoded by a gene in the RD1 locus, which is essential for the bacterium's ability to cause disease. While its exact molecular function is still being studied, Tb7.7 is thought to be involved in bacterial secretion or modulation of host cell signaling pathways, helping Mycobacterium tuberculosis evade host immune clearance and establish intracellular infection. Tb7.7 exhibits strong immunogenicity, stimulating specific T-cell responses in individuals with tuberculosis. This property makes it a potential candidate for tuberculosis vaccines, as it can target virulence mechanisms critical for bacterial survival. It also has potential as a diagnostic marker, as Tb7.7-specific immune responses can be detected in infected individuals, supporting the identification of latent or active infections.
- Alternative Names
- M. tuberculosis Tuberculosis Protein 7.7, Mtb Tb7.7
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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