Recombinant Anti-S. pneumoniae ply Biparatopic Antibody, Tandem scFv (Clone PLY-4 x Clone PLY-7) (CAT#: VS-0525-YC159)
Recombinant Anti-S. pneumoniae ply Biparatopic Antibody, Tandem scFv (Clone PLY-4 x Clone PLY-7) is a biparatopic antibody (bpAb) binding two distinct epitopes of S. pneumoniae Ply. This construct was designed as a tandem scFv. It features the PLY-4 scFv N-terminally fused to the PLY-7 scFv. PLY-4 recognizes a conformation-dependent epitope involving R232, whereas PLY-7 binds to the region comprising amino acids 401-407 (GQDLTAH).
Specific Inquiry
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- Streptococcus pneumoniae Ply
- Species Reactivity
- S. pneumoniae
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- PLY-4
- Clone 2
- PLY-7
- Epitope 1
- A conformation-dependent epitope with a core reactivity involving R232
- Epitope 2
- aa 401-407, GQDLTAH
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, WB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- S. pneumoniae Pneumolysin
Target
- Introduction
- Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. It is a pore-forming toxin of 53 kDa composed of 471 amino acids. It has a range of biological activity, including the ability to lyse and interfere with the function of cells and soluble molecules of the immune system.
- Alternative Names
- Pneumolysin; PLY
- Gene ID
- 933687
- UniProt ID
- Q7ZAK5
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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