Rabbit Anti-Staphylococcus aureus Enolase Antibody (VS-0925-XY57)
CAT#: VS-0925-XY57
Staphylococcus aureus Enolase antibodies recognize this glycolytic enzyme, enabling Western blotting, immunoprecipitation to study plasminogen binding, and studies on its dual role in metabolism and adhesion. Useful for researching Staphylococcus aureus tissue invasion.
Specifications
- Host Animal
- Rabbit
- Applications
- WB
- Specificity
- Staphylococcus aureus Enolase
- Target
- Staphylococcus aureus Enolase
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Protein G Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 50% glycerol
- Preservative
- 0.03% ProClin 300
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Staphylococcus aureus Enolase is a metabolic enzyme and cell surface protein of Staphylococcus aureus. Primarily, it functions in the glycolytic pathway, catalyzing the conversion of 2-phosphoglycerate to phosphoenolpyruvate-an essential step for energy production, supporting bacterial growth and survival. Beyond its metabolic role, Enolase is also localized to the bacterial cell surface, where it acts as an adhesin, binding to host extracellular matrix proteins (e.g., plasminogen). This binding activates plasminogen to plasmin, a protease that degrades host tissues, facilitating bacterial invasion and spread. Enolase exhibits immunogenicity, stimulating host immune responses that can target both the metabolic and adhesive functions of the protein. It is a potential target for anti-staphylococcal drugs and vaccines: drugs inhibiting Enolase may disrupt glycolysis, while vaccines targeting Enolase may block adhesion and tissue invasion, reducing infection severity.
- Alternative Names
- S. aureus Enolase Enzyme, Sa Enolase
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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