Recombinant Anti-HCV Core Protein (AA 33-37 x AA 71-77) Biparatopic Antibody, Tandem scFv (Clone DA3 x Clone 2G3)
CAT#: VS-0525-YC93
The Recombinant Anti-HCV Core Protein (AA 33-37 x AA 71-77) Biparatopic Antibody, Tandem scFv (Clone DA3 x Clone 2G3) serves as a biparatopic antibody (bpAb) that engages two distinct HCV Core Protein epitopes. This bpAb's tandem scFv structure incorporates the DA3 scFv (specific for amino acids 33-37) N-terminally linked to the 2G3 scFv (binding amino acids 71-77).
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- HCV core protein
- Species Reactivity
- HCV
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- DA3
- Clone 2
- 2G3
- Epitope 1
- aa 33-37
- Epitope 2
- aa 71-77
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HCV core protein
Target
- Introduction
- Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. Hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (Hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. The core protein has 191 amino acids and can be divided into three domains on the basis of hydrophobicity: domain 1 (residues 1-117) contains mainly basic residues with two short hydrophobic regions; domain 2 (residues 118-174) is less basic and more hydrophobic and its C-terminus is at the end of p21; domain 3 (residues 175-191) is highly hydrophobic and acts as a signal sequence for E1 envelope protein.
- Alternative Names
- Hepatitis C virus; HCV; Hepatitis C virus core protein; HCV core protein
- Gene ID
- 951475
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| CAT | Product Name | Application | Type |
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| VS-0525-YC92 | Recombinant Anti-HCV Core Protein (AA 28-32 x AA 33-37) Biparatopic Antibody, Tandem scFv (Clone CA7 x Clone DA3) | ELISA, IB, IP | Tandem scFv |
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