Recombinant Anti-HCV Core Protein (AA 33-37 x AA 71-77) Biparatopic Antibody, Tandem scFv (Clone DA3 x Clone 2G3) (CAT#: VS-0525-YC93)
The Recombinant Anti-HCV Core Protein (AA 33-37 x AA 71-77) Biparatopic Antibody, Tandem scFv (Clone DA3 x Clone 2G3) serves as a biparatopic antibody (bpAb) that engages two distinct HCV Core Protein epitopes. This bpAb's tandem scFv structure incorporates the DA3 scFv (specific for amino acids 33-37) N-terminally linked to the 2G3 scFv (binding amino acids 71-77).
Specific Inquiry
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- HCV core protein
- Species Reactivity
- HCV
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- DA3
- Clone 2
- 2G3
- Epitope 1
- aa 33-37
- Epitope 2
- aa 71-77
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HCV core protein
Target
- Introduction
- Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. Hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (Hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. The core protein has 191 amino acids and can be divided into three domains on the basis of hydrophobicity: domain 1 (residues 1-117) contains mainly basic residues with two short hydrophobic regions; domain 2 (residues 118-174) is less basic and more hydrophobic and its C-terminus is at the end of p21; domain 3 (residues 175-191) is highly hydrophobic and acts as a signal sequence for E1 envelope protein.
- Alternative Names
- Hepatitis C virus; HCV; Hepatitis C virus core protein; HCV core protein
- Gene ID
- 951475
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Biparatopic Antibody (bpAb) Products
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-943 | Recombinant Human Anti-HCV Core Protein Antibody scFv Fragment | ELISA, PP, WB, IF, Inhib | scFv |
FAMAB-0298JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone CA7); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0299JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone 2H9); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0300JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone DA3); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0357JF-S(P) | Human Anti-HCV Core Protein Recombinant Antibody (clone 4C2); scFv Fragment | ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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