Recombinant Anti-HIV1 p24 (AA 142-156 x AA 207-216) Biparatopic Antibody, Tandem scFv (Clone CB-mab-p24/13 x Clone BB128) (CAT#: VS-0525-YC102)
The Recombinant Anti-HIV1 p24 (AA 142-156 x AA 207-216) Biparatopic Antibody, Tandem scFv (Clone CB-mab-p24/13 x Clone BB128) is a biparatopic antibody (bpAb) specifically designed to bind two distinct HIV1 p24 epitopes. Its tandem scFv configuration involves the N-terminal fusion of the CB-mab-p24/13 scFv (recognizing amino acids 142-156, VHQAISPRTLNAWVK) to the BB128 scFv (targeting amino acids 207-216, EAAEWDRVHP).
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- HIV1 p24
- Species Reactivity
- HIV1
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- CB-mab-p24/13
- Clone 2
- BB128
- Epitope 1
- aa 142-156, VHQAISPRTLNAWVK
- Epitope 2
- aa 207-216, EAAEWDRVHP
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HIV-1 p24 antigen
Target
- Introduction
- HIV can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the endangered west African primate sooty mangabey. HIV1 viruses may be further divided into groups. The HIV1 group M viruses predominate and are responsible for the AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data. Some of the subtypes are known to be more virulent or are resistant to different medications. Likewise, HIV-2 viruses are thought to be less virulent and transmissible than HIV1 M group viruses, although HIV-2 is known to cause AIDS.
- Alternative Names
- HIV1 p24; Human immunodeficiency virus p24
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
VS3-WK1331 | Mouse Anti-HIV1 p24 Recombinant Antibody (VS3-WK1331) | ELISA | Mouse IgG |
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