Recombinant Anti-HIV1 p24 (AA 142-156 x AA 207-216) Biparatopic Antibody, Tandem scFv (Clone CB-mab-p24/13 x Clone BB128)

CAT#: VS-0525-YC102

The Recombinant Anti-HIV1 p24 (AA 142-156 x AA 207-216) Biparatopic Antibody, Tandem scFv (Clone CB-mab-p24/13 x Clone BB128) is a biparatopic antibody (bpAb) specifically designed to bind two distinct HIV1 p24 epitopes. Its tandem scFv configuration involves the N-terminal fusion of the CB-mab-p24/13 scFv (recognizing amino acids 142-156, VHQAISPRTLNAWVK) to the BB128 scFv (targeting amino acids 207-216, EAAEWDRVHP).

Specifications

  • Host Animal 1
  • Mouse
  • Host Animal 2
  • Mouse
  • Specificity
  • HIV1 p24
  • Species Reactivity
  • HIV1
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • CB-mab-p24/13
  • Clone 2
  • BB128
  • Epitope 1
  • aa 142-156, VHQAISPRTLNAWVK
  • Epitope 2
  • aa 207-216, EAAEWDRVHP
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • HIV-1 p24 antigen

Target

  • Introduction
  • HIV can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the endangered west African primate sooty mangabey. HIV1 viruses may be further divided into groups. The HIV1 group M viruses predominate and are responsible for the AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data. Some of the subtypes are known to be more virulent or are resistant to different medications. Likewise, HIV-2 viruses are thought to be less virulent and transmissible than HIV1 M group viruses, although HIV-2 is known to cause AIDS.
  • Alternative Names
  • HIV1 p24; Human immunodeficiency virus p24
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