Human Anti-hMPV F Vaccinal Antibody (VS-0625-XY49)
CAT#: VS-0625-XY49
This vaccinal antibody targets hMPV F, suitable for ELISA and neutralization (Neut). It features Fc segment engineering to induce vaccine-like effects and enhance antiviral activity by boosting effector functions, optimizing half-life, and improving viral neutralization potency.
Specifications
- Target
- hMPV F
- Host Animal
- Human
- Applications
- ELISA; Neut
- Specificity
- hMPV F
- Species Reactivity
- hMPV
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Epitope
- Located across antigenic sites II and V
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Human metapneumovirus (hMPV) is a leading cause of respiratory disease in children and the elderly. Initially identified in 2001 in samples collected from children with respiratory tract infection in the Netherlands, the clinical features of hMPV are similar to those of respiratory syncytial virus and include mid-to-upper respiratory tract infection that may require hospitalization. The hMPV F protein is a trimeric class I viral fusion protein that has high conserva_x0002_tion between viral subgroups (A1, A2, B1, and B2). hMPV can infect respiratory epithelial cells in the absence of the hMPV G protein, although hMPV G is required for viral fitness in vivo. The hMPV F protein contains an RGD motif, and the receptor has been hypothesized to be α5β1 integrin. Heparan sulfate has also been shown to have a role in hMPV F protein-mediated attachment.
- Related Disease
- Respiratory disease
- Alternative Names
- Human metapneumovirus fusion protein
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "HMPV F"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1119-CN | Recombinant Human Anti-HMPV F Antibody (EV046113) | ELISA | Human IgG1, κ |
| HPAB-1120-CN | Recombinant Human Anti-HMPV F Antibody (EV046143) | ELISA | Human IgG1, κ |
| HPAB-1121-CN | Recombinant Human Anti-HMPV F Antibody (EV046135) | ELISA | Human IgG1, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1119-CN-S(P) | Recombinant Human Anti-HMPV F Antibody scFv Fragment (EV046113) | ELISA | Human scFv |
| HPAB-1120-CN-S(P) | Recombinant Human Anti-HMPV F Antibody scFv Fragment (EV046143) | ELISA | Human scFv |
| HPAB-1121-CN-S(P) | Recombinant Human Anti-HMPV F Antibody scFv Fragment (EV046135) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1119-CN-F(E) | Recombinant Human Anti-HMPV F Antibody Fab Fragment (EV046113) | ELISA | Human Fab |
| HPAB-1120-CN-F(E) | Recombinant Human Anti-HMPV F Antibody Fab Fragment (EV046143) | ELISA | Human Fab |
| HPAB-1121-CN-F(E) | Recombinant Human Anti-HMPV F Antibody Fab Fragment (EV046135) | ELISA | Human Fab |
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