Human Anti-IAV NA Vaccinal Antibody (VS-0625-XY54)

CAT#: VS-0625-XY54

Targeted at IAV neuraminidase (NA), this vaccinal antibody supports ELISA, SPR, neutralization (Neut), and inhibition (Inhib) assays. Fc segment engineering induces vaccine-like effects and enhances antiviral efficacy by optimizing Fc effector functions.

Specifications

  • Target
  • IAV NA
  • Host Animal
  • Human
  • Applications
  • ELISA; SPR; Neut; Inhib
  • Specificity
  • IAV NA
  • Species Reactivity
  • IAV
  • Type
  • Human IgG
  • Purity
  • >95%, determined by SDS-PAGE
  • Purification
  • Protein A purified
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Target

  • Introduction
  • Influenza A viruses cause considerable morbidity and mortality annually, posing threats to public health worldwide. Monoclonal antibodies represent a viable approach for the treatment of influenza. Antibodies targeting hemagglutinin (HA) and neuraminidase (NA), the two important surface glycoproteins of influenza virus, can disrupt viral entry into host cells and block viral egress or prevent virus from budding, respectively. Earlier work defined the structure of NA and NA-fragment antigen-binding (Fab) complexes and demonstrated the protective effects of immune responses to NA.
  • Related Disease
  • Influenza
  • Alternative Names
  • Influenza virus Neuraminidase
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Datasheet

MSDS

COA

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Secondary Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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