Human Anti-LCMV GP Vaccinal Antibody (VS-0625-XY58)
CAT#: VS-0625-XY58
This vaccinal antibody targets LCMV GP and is validated for ELISA, BLI, and neutralization (Neut) assays. Engineered with Fc segment modifications, it induces vaccine-like effects by enhancing immune cell activation and boosts antiviral efficacy through improved Fc effector functions, making it suitable for both research and potential therapeutic applications.
Specifications
- Target
- LCMV GP
- Host Animal
- Human
- Applications
- ELISA; BLI; Neut
- Specificity
- LCMV GP
- Species Reactivity
- LCMV
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- The mammarenavirus lymphocytic choriomeningitis virus (LCMV) is a globally distributed zoonotic pathogen that can be lethal in immunocompromised patients and can cause severe birth defects if acquired during pregnancy. The envelope glycoproteins of LCMV (LCMV GP) are initially expressed as a precursor polypeptide, GP-C, which is posttranslationally processed by a cellular protease into GP-1 and GP-2. GP-1 interacts with the cellular receptor for LCMV, which has been identified as alpha-dystroglycan. GP-2 contains the fusion peptide and the transmembrane domain.
- Related Disease
- severe birth defects
- Alternative Names
- lymphocytic choriomeningitis virus glycoprotein
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "LCMV GP"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0348-YC | Human Anti-LCMV GP Recombinant Antibody (HPAB-N0348-YC) | ELISA, Neut | Human IgG |
| VS-0923-XY19 | Recombinant Human Anti-LCMV GP Antibody (clone 18.5C-M28) | ELISA, BLI, Neut | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0348-YC-S(P) | Human Anti-LCMV GP Recombinant Antibody; scFv Fragment (HPAB-N0348-YC-S(P)) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0348-YC-F(E) | Human Anti-LCMV GP Recombinant Antibody; Fab Fragment (HPAB-N0348-YC-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0969 | PE-H-2Db/LCMV GP (CSANNSHHYI) MHC Tetramer | FCM, IHC | |
| MHC-CN0970 | APC-H-2Db/LCMV GP (CSANNSHHYI) MHC Tetramer | FCM, IHC | |
| MHC-CN0971 | FITC-H-2Db/LCMV GP (CSANNSHHYI) MHC Tetramer | FCM, IHC | |
| MHC-CN0972 | H-2Db/LCMV GP (CSANNSHHYI) MHC Tetramer | FCM, IHC | |
| MHC-CN0973 | PE-A*02:01/LCMV GP (ALPHIIDEV) MHC Tetramer | FCM, IHC |
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