Anti-LDH (clone W24V157) Recombinant Antibody Coupled Liposome (VS-1024-FY158)
CAT#: VS-1024-FY158
Antibody-conjugated liposomes designed to target lactate dehydrogenase (LDH) represent a novel therapeutic approach aimed at effectively modulating tumor growth and counteracting immune suppression within the tumor microenvironment. By specifically delivering therapeutic agents to the tumor site, these liposomes can influence critical immune factors that play a role in leukemia progression, potentially leading to enhanced immune responses against the cancer. This innovative strategy not only highlights the importance of targeted therapy in oncology but also aims to significantly improve the prognosis and overall survival rates of patients diagnosed with leukemia.
More Infomation
Specifications
- Potential Clinical Applications
- Leukaemia
Product Composition
- Clone
- W24V157
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was specifically engineered to target lactate dehydrogenase (LDH). Lactate dehydrogenase is an enzyme that plays a crucial role in the conversion of pyruvate to lactate in the glycolytic pathway, which is vital for cellular metabolism.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- LDH
- Full Name
- Lactate Dehydrogenase
- Sequence Similarities
- Belongs to the LDH/MDH superfamily.
- Cellular Localization
- Cytoplasm; Mitochondrion inner membrane; Peripheral membrane protein
- Post Translation Modifications
- Ubiquitination at Lys7, Lys60, Lys77, Lys82, Lys91, Lys119, Lys233, Lys308, Lys310, Lys319, Lys329, and Lys332 ( NX_P07195 [NX_P07195-1] )
Modification sites at PhosphoSitePlus ( P07195 )
Glycosylation from GlyGen (P07195) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_006719137.1; XP_054228021.1; NP_001167568.1; NP_001302466.1; NP_001401162.1
- Function
- Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1141WJ | Recombinant Camel Anti-LDH Single Domain Antibody (HPAB-1141WJ) | ELISA, Inhib | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1142WJ | Recombinant Camel Anti-LDH Single Domain Antibody (HPAB-1142WJ) | Inhib | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1143WJ | Recombinant Camel Anti-LDH Single Domain Antibody (HPAB-1143WJ) | ELISA | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-FY632 | Mouse Anti-ldh Recombinant Antibody (clone 2506W0527) | ELISA | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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