AbPlus™ Anti-MAP2K1 Magnetic Beads (CBACN-357)
CAT#: VS-0424-XY180
The AbPlus Anti-MAP2K1 Magnetic Beads (CBACN-357) is an innovative affinity resin which is bound with anti-MAP2K1 specific antibody (CBACN-357). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MAP2K1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26430/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3834/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows moderate cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26430/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human stomach
Immunohistochemical staining of human stomach shows moderate cytoplasmic and nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3834/ihc_selected.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26430/57722_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26430/57722_A_8_3.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26430/57722_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169032-MAP2K1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-MAP2K1 specific antibody (CBACN-357)
- Target
- MAP2K1
- Immunogen
- Human MAP2K1 (aa 1-100)
- Target Species
- Human, Mouse, Rat, Cattle, Dog
- Antibody Clone
- CBACN-357
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
- Alternative Names
- Mitogen-Activated Protein Kinase Kinase 1; ERK Activator Kinase 1; MAPK/ERK Kinase 1; EC 2.7.12.2; MAPKK 1; PRKMK1; MEK 1; MEK1
- Gene ID
- 5604
- UniProt ID
- Q02750
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MAP2K1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1129CT | Recombinant Mouse anti-Human MAP2K1 Monoclonal antibody (8G2) | IP, WB | |
| ZG-0451U | Rabbit Anti-Phospho-MAP2K1 (T292) Recombinant Antibody (clone 4E7) | ELISA, WB | Rabbit IgG |
| ZG-0452U | Rabbit Anti-MAP2K1 Recombinant Antibody (clone 3F10) | ELISA, WB, IHC, IP | Rabbit IgG |
| ZG-0453U | Rabbit Anti-MAP2K1 Recombinant Antibody (clone 9B6) | ELISA, WB, IHC, IP | Rabbit IgG |
| VS3-FY2793 | Rabbit Anti-MAP2K1 Recombinant Antibody (VS3-FY2793) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0340MZ | Chicken Anti-MAP2K1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2131 | Hi-Affi™ Recombinant Rabbit Anti-MAP2K1 Monoclonal Antibody (DS2131AB) | ICC, IHC-P, IP, WB | IgG |
| MOR-4693 | Hi-Affi™ Recombinant Rabbit Anti-MAP2K1 Monoclonal Antibody (TH207DS) | WB, ChIP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC941 | AbPlus™ Anti-MAP2K1 Magnetic Beads (VS-0724-YC941) | IP, Protein Purification | |
| VS-0724-YC968 | AbPlus™ Anti-Map2k1 Magnetic Beads (VS-0724-YC968) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4205 | Anti-MAP2K1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4206 | Anti-Mouse MAP2K1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4207 | Anti-Rat MAP2K1 Immunohistochemistry Kit | IHC |
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