Anti-NAPSA (clone W24V220) Recombinant Antibody Coupled Liposome (VS-1024-FY217)
CAT#: VS-1024-FY217
Lipid nanoparticles conjugated with anti-NAPSA antibodies show great potential in ovarian cancer research. First, they can specifically target tumor cells, significantly improving the delivery efficiency of drugs. Second, this targeting mechanism may reduce damage to healthy cells, thereby alleviating treatment side effects. Finally, lipid nanoparticles combined with anti-NAPSA antibodies are expected to enhance treatment outcomes for ovarian cancer patients and promote the development of personalized therapy.
Gene Expression
Normal Tissue
Figure 1 High expression in lung
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45280/ihc_selected.jpg
Normal Tissue
Figure 2 Low expression in placenta
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45280/121166_A_2_7_val_selected.jpg
Normal Tissue
Figure 3 Lung
Alveolar cells type Alveolar cells type I I Staining: High Intensity: Strong Quantity:>75% Macrophages Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47744/121159_A_1_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47744/121159_A_9_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000131400-NAPSA
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More Infomation
Specifications
- Potential Clinical Applications
- Ovarian cancer
Product Composition
- Clone
- W24V220
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was meticulously developed to bind to NAPSA, an essential protein implicated in various cellular processes. The targeted binding of this antibody to NAPSA may aid in investigating its function and role in diseases, including cancer. Through its precise interactions, this antibody holds promise for advancing research into potential therapeutic strategies that could manipulate NAPSA activity for clinical benefit.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- NAPSA
- Introduction
- This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma.
- Alternative Names
- Napsin A Aspartic Peptidase; Kidney-Derived Aspartic Protease-Like Protein; Aspartyl Protease 4; TA01/TA02; Napsin-1; Asp 4; NAP1; ASP4; NAPA; EC 3.4.23.15
- Full Name
- Napsin A Aspartic Peptidase
- Gene ID
- 9476
- UniProt ID
- O96009
- Sequence Similarities
- Belongs to the peptidase A1 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn90, Asn133, and Asn336 (NX_O96009 [NX_O96009-1])
Modification sites at PhosphoSitePlus (O96009)
Glycosylation from GlyGen (O96009) 3 sites
- Protein Refseq
- XP_016883001.1; XP_054178683.1; XP_054178684.1; NP_004842.1
- Function
- May be involved in processing of pneumocyte surfactant precursors.
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Datasheet
MSDS
COA
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See other products for "NAPSA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2239MZ | Recombinant Mouse Anti-Human NAPSA Antibody (clone LDH2.2) | IHC-P | Mouse antibody |
| MOB-0137F | Mouse Anti-NAPSA Recombinant Antibody (MOB-0137F) | IHC-P, IF | Mouse IgG |
| MOB-0138F | Mouse Anti-NAPSA Recombinant Antibody (MOB-0138F) | IHC-P, IF | Mouse IgG |
| ZG-0400U | Rabbit Anti-NAPSA Recombinant Antibody (clone L23-Q) | IHC-P | Rabbit IgG |
| VS3-XY1134 | Mouse Anti-NAPSA Recombinant Antibody (clone 10C4B8) | ELISA, WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2365 | Hi-Affi™ Recombinant Rabbit Anti-NAPSA Monoclonal Antibody (DS2365AB) | WB, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4692 | Anti-NAPSA Immunohistochemistry Kit | IHC |
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