AbPlus™ Anti-NELFB Magnetic Beads (VS-0724-YC778) (CAT#: VS-0724-YC778)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-NELFB specific antibody

• Target
• NELFB

• Immunogen
• Recombinant human COBRA1/NELFB fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]

• Alternative Names
• Negative Elongation Factor Complex Member B; Cofactor Of BRCA1; COBRA1; NELF-B; Negative Elongation Factor Protein B; Negative Elongation Factor B; KIAA1182;

• Gene ID
• 25920

• UniProt ID
• Q8WX92

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