Recombinant Anti-NHBA (AA 73-82 x AA 243-274) Biparatopic Antibody, Tandem scFv (Clone 12E1 x Clone 10C3)

CAT#: VS-0525-YC138

The Recombinant Anti-NHBA (AA 73-82 x AA 243-274) Biparatopic Antibody, Tandem scFv (Clone 12E1 x Clone 10C3) is a biparatopic antibody (bpAb) designed for dual binding to distinct epitopes of NHBA. Its tandem scFv structure incorporates the 12E1 scFv (targeting amino acids 73-82, AAVSEENTGN) N-terminally fused to the 10C3 scFv (specific for amino acids 243-274, KSEFEKLSDADKISNYKKDGKNDGKNDKFVGL).

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • N. meningitidis Neisserial heparin-binding antigen
  • Species Reactivity
  • N. meningitidis
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • 12E1
  • Clone 2
  • 10C3
  • Epitope 1
  • aa 73-82, AAVSEENTGN
  • Epitope 2
  • aa 243-274, KSEFEKLSDADKISNYKKDGKNDGKNDKFVGL
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, WB
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Neisserial heparin-binding antigen

Target

  • Introduction
  • Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein specific for Neisseria and constitutes one of the three main protein antigens of the Bexsero vaccine.
  • Alternative Names
  • NHBA; Neisserial heparin-binding antigen
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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