AbPlus™ Anti-NOX4 Magnetic Beads (VS-0724-YC705)

CAT#: VS-0724-YC705

The AbPlus Anti-NOX4 Magnetic Beads (VS-0724-YC705) is an innovative affinity resin which is bound with anti-NOX4 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of NOX4 protein under native and denaturing conditions.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-NOX4 specific antibody
  • Target
  • NOX4
  • Immunogen
  • Synthetic peptide corresponding to the C-terminus of the human NOX4.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
  • Alternative Names
  • NADPH Oxidase 4; Kidney Superoxide-Producing NADPH Oxidase; Renal NAD(P)H-Oxidase; Kidney Oxidase-1; KOX-1; RENOX; EC 1.6.3.-; EC 1.6.3; KOX;
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