Anti-NUCB2 (clone NAP37) Recombinant Antibody Coupled Liposome (VS-1024-FY302)
CAT#: VS-1024-FY302
Anti-Nucb2 antibody conjugated liposomes hold significant potential in prostate cancer research by enabling targeted delivery of therapeutic agents directly to cancer cells expressing the Nucb2 antigen, thereby enhancing treatment efficacy while minimizing off-target effects. Additionally, these liposomes can serve as valuable tools for diagnostic applications, facilitating the visualization and tracking of prostate cancer progression in vivo.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8395/if_selected.jpg
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More Infomation
Specifications
- Potential Clinical Applications
- Prostate cancer
Product Composition
- Clone
- NAP37
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This antibody is a recombinant mouse monoclonal that was specifically engineered to target Nucb2. It is designed to recognize and bind with high affinity to Nucb2, facilitating various research applications. By utilizing this monoclonal antibody, researchers can gain deeper insights into the biological functions of Nucb2 in cellular processes and disease mechanisms.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- NUCB2
- Introduction
- Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Increased nesfatin-1 in the hypothalamus contributes to diminished hunger, a 'sense of fullness', and a potential loss of body fat and weight.
- Alternative Names
- Nesfatin-1
- Full Name
- Nucleobindin 2
- Gene ID
- 4925
- UniProt ID
- P80303
- Sequence Similarities
- Belongs to the nucleobindin family.
- Cellular Localization
- Golgi apparatus; Membrane; Peripheral membrane protein; Cytoplasm; Secreted; Endoplasmic reticulum; Nucleus envelope
- Post Translation Modifications
- Glycosylation at Ser42, Ser96, Thr163, Thr172, Thr314, Thr322, Tyr389, and Ser408 ( NX_P80303 [NX_P80303-1] )
Ubiquitination at Lys90 and Lys247 ( NX_P80303 [NX_P80303-1] )
Modification sites at PhosphoSitePlus ( P80303 )
Glycosylation from GlyGen (P80303) 11 sites, 3 O-linked glycans (10 sites)
- Protein Refseq
- XP_016873301.1; XP_016873302.1; XP_016873303.1; XP_016873306.1; XP_016873307.1
- Function
- Calcium-binding protein which may have a role in calcium homeostasis (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3 (By similarity).
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone NAP37"
- CAT
- Product Name
See other products for "Nucb2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1826-sdAb | Recombinant Anti-Human Nucb2 VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2318z | Mouse Anti-NUCB2 Recombinant Antibody (clone 21F9) | WB, ELISA | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2513 | Hi-Affi™ Recombinant Rabbit Anti-NUCB2 Monoclonal Antibody (DS2513AB) | WB, IHC-P, ICC, IF, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1151 | AbPlus™ Anti-NUCB2 Magnetic Beads (VS-0724-YC1151) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5030 | Anti-NUCB2 Immunohistochemistry Kit | IHC |
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