AbPlus™ Anti-PRKCA Magnetic Beads (CBACN-450)

CAT#: VS-0424-XY216

The AbPlus Anti-PRKCA Magnetic Beads (CBACN-450) is an innovative affinity resin which is bound with anti-PRKCA specific antibody (CBACN-450). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PRKCA protein under native and denaturing conditions.

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-PRKCA specific antibody (CBACN-450)
  • Target
  • PRKCA
  • Immunogen
  • C-terminus of human PRKCA
  • Target Species
  • Human, Mouse, Rat
  • Antibody Clone
  • CBACN-450
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
  • Alternative Names
  • AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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