Recombinant Anti-Respiratory Syncytial Virus F Biparatopic Antibody, Tandem scFv (Clone R4.C6 x Clone C57)

CAT#: VS-0525-YC157

This biparatopic antibody (bpAb) targets two distinct epitopes on Respiratory Syncytial Virus F. Its tandem scFv architecture involves the N-terminal fusion of the R4.C6 scFv to the C57 scFv. The R4.C6 scFv recognizes an intermediate position between antigenic sites II and IV in the F1 fragment, while the C57 scFv specifically targets antigenic site II of the fusion protein.

Specifications

  • Host Animal 1
  • Mouse
  • Host Animal 2
  • Human
  • Specificity
  • Respiratory Syncytial Virus F
  • Species Reactivity
  • Respiratory Syncytial Virus
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • R4.C6
  • Clone 2
  • C57
  • Epitope 1
  • An intermediate position between antigenic sites II and IV in the F1 fragment
  • Epitope 2
  • Antigenic site II of Fusion protein
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Respiratory Syncytial Virus fusion protein

Target

  • Introduction
  • The Respiratory Syncytial Virus fusion glycoprotein is a major target for vaccine development.
  • Alternative Names
  • Human respiratory syncytial virus fusion protein; Human respiratory syncytial virus; fusion protein; F protein; Respiratory Syncytial Virus fusion (F) glycoprotein; fusion glycoprotein
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