AbPlus™ Anti-SERPINB3 Magnetic Beads (VS-0724-YC615) (CAT#: VS-0724-YC615)
The AbPlus Anti-SERPINB3 Magnetic Beads (VS-0724-YC615) is an innovative affinity resin which is bound with anti-SERPINB3 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SERPINB3 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36006/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36006/if_selected.jpg

Figure 2 High expression in esophagus.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_B_4_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_B_4_1_val_selected.jpg

Figure 3 Low expression in liver.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_A_8_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_A_8_4_val_selected.jpg

Figure 4 Cervix
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_B_9_3.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18772/42109_B_9_3.jpg

Figure 5 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, SiHa, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000057149-SERPINB3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000057149-SERPINB3
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SERPINB3 specific antibody
- Target
- SERPINB3
- Immunogen
- Recombinant human SERPINB3/SCCA-1, aa 2-390.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- SERPINB3 (Serpin Family B Member 3) is a Protein Coding gene. Diseases associated with SERPINB3 include Anus Cancer and Cervical Squamous Cell Carcinoma. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB4.
- Alternative Names
- Serpin Family B Member 3; Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 3; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3; Squamous Cell Carcinoma Antigen 1; Protein T4-A; SCCA-1; SCCA1; Serpin B3;
- Gene ID
- 6317
- UniProt ID
- P29508
Downloads
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MOB-3589z | Mouse Anti-SERPINB3 Recombinant Antibody (clone 21B12) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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