AbPlus™ Anti-SUN2 Magnetic Beads (VS-0424-XY250) (CAT#: VS-0424-XY250)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-SUN2 specific antibody

• Target
• SUN2

• Immunogen
• GST-Sun2 peptide

• Target Species
• Human

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM).

• Alternative Names
• UNC84B; rab5IP; SUN domain-containing protein 2; Sad1 unc-84 domain protein 2 nuclear envelope protein unc-84 homolog B rab5-interacting protein sad1/unc-84 protein-like 2 unc-84 homolog B

• Gene ID
• 25777

• UniProt ID
• Q9UH99

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