AbPlus™ Anti-SUN2 Magnetic Beads (VS-0424-XY250)
CAT#: VS-0424-XY250
The AbPlus Anti-SUN2 Magnetic Beads (VS-0424-XY250) is an innovative affinity resin which is bound with anti-SUN2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SUN2 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human heart muscle
Immunohistochemical staining of human heart muscle shows strong nuclear membrane positivity in myocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_A_5_6.jpg
Normal Tissue
Figure 7 Heart
Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_B_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1209/3387_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100242-SUN2/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-SUN2 specific antibody
- Target
- SUN2
- Immunogen
- GST-Sun2 peptide
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM).
- Alternative Names
- UNC84B; rab5IP; SUN domain-containing protein 2; Sad1 unc-84 domain protein 2 nuclear envelope protein unc-84 homolog B rab5-interacting protein sad1/unc-84 protein-like 2 unc-84 homolog B
- Gene ID
- 25777
- UniProt ID
- Q9UH99
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CITATIONS
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SUN2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1678z | Mouse Anti-SUN2 Recombinant Antibody (clone 32F4) | WB, ELISA, IF, IP | Mouse IgG2a, κ |
| MRO-1455-CN | Recombinant Rabbit Anti-SUN2 Monoclonal Antibody (JG39-52) | WB, IHC, FC, IF | Rabbit IgG |
| VS1-YJ209 | Rabbit Anti-SUN2 Antibody (VS-0722-YJ209) | IB, IF | Rabbit IgG |
| VS1-YJ210 | Rabbit Anti-SUN2 Antibody (VS-0722-YJ210) | IB, IF, WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3465 | Hi-Affi™ Recombinant Rabbit Anti-SUN2 Monoclonal Antibody (DS3465AB) | WB, IHC, ICC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7027 | Anti-SUN2 Immunohistochemistry Kit | IHC |
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