AbPlus™ Anti-TFPI2 Magnetic Beads (VS-0724-YC763)
CAT#: VS-0724-YC763
The AbPlus Anti-TFPI2 Magnetic Beads (VS-0724-YC763) is an innovative affinity resin which is bound with anti-TFPI2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of TFPI2 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Placenta
Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Hofbauer cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10142/25813_A_2_7.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105825-TFPI2/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-TFPI2 specific antibody
- Target
- TFPI2
- Immunogen
- Recombinant human TAB1 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Alternative Names
- TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1; TAK1-Binding Protein 1; Mitogen-Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1; Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 1; MAP3K7IP1; Transforming Growth Factor Beta-Activated Kinase-Binding Protein 1;
- Gene ID
- 10454
- UniProt ID
- Q15750
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TFPI2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3597z | Mouse Anti-TFPI2 Recombinant Antibody (clone 20B6) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| MOB-2016CT | Recombinant Mouse anti-Human TFPI2 Monoclonal antibody (EML776) | IHC-P |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1998CQ | Mouse Anti-TFPI2 Recombinant Antibody (clone CBL592) | IP, Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7199 | Anti-TFPI2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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