AbPlus™ Anti-VRK1 Magnetic Beads (VS-0724-YC137) (CAT#: VS-0724-YC137)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-VRK1 specific antibody

• Target
• VRK1

• Immunogen
• Recombinant human VRK1, aa 1-396.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]

• Alternative Names
• Vaccinia Related Kinase 1; EC 2.7.11.1; Serine/Threonine-Protein Kinase VRK1; Vaccinia Virus B1R-Related Kinase 1; Vaccinia-Related Kinase 1; PCH1A; PCH1;

• Gene ID
• 7443

• UniProt ID
• Q99986

Select a product category from the dropdown menu below to view related products.