AbPlus™ Anti-VRK1 Magnetic Beads (VS-0724-YC137)
CAT#: VS-0724-YC137
The AbPlus Anti-VRK1 Magnetic Beads (VS-0724-YC137) is an innovative affinity resin which is bound with anti-VRK1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of VRK1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/660/if_selected.jpg
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-VRK1 specific antibody
- Target
- VRK1
- Immunogen
- Recombinant human VRK1, aa 1-396.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
- Alternative Names
- Vaccinia Related Kinase 1; EC 2.7.11.1; Serine/Threonine-Protein Kinase VRK1; Vaccinia Virus B1R-Related Kinase 1; Vaccinia-Related Kinase 1; PCH1A; PCH1;
- Gene ID
- 7443
- UniProt ID
- Q99986
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "VRK1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2228CT | Recombinant Mouse anti-Human VRK1 Monoclonal antibody (EML2135) | WB | |
| VS3-QX1239 | Mouse Anti-VRK1 Recombinant Antibody (clone 1015CT2.1.1) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3853 | Rabbit Anti-VRK1 Recombinant Antibody (clone DS3853AB) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0189LC | Mouse Anti-VRK1 Recombinant Antibody (clone 1B5) | IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7872 | Anti-VRK1 Immunohistochemistry Kit | IHC |
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