AbPlus™ Anti-XRCC1 Magnetic Beads (VS-0724-YC167)

CAT#: VS-0724-YC167

The AbPlus Anti-XRCC1 Magnetic Beads (VS-0724-YC167) is an innovative affinity resin which is bound with anti-XRCC1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of XRCC1 protein under native and denaturing conditions.

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-XRCC1 specific antibody
  • Target
  • XRCC1
  • Immunogen
  • Recombinant human XRCC1 fragment derived from E. coli.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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