BV421-DRB1*04:01/Human GAD65 (KGMAALPRLIAFTSEHSHFS) MHC Tetramer (CAT#: MHC-YF1466)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed GAD65-derived peptide of KGMAALPRLIAFTSEHSHFS sequence covering 265-284 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
Figure 2 Pancreas
(Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
(Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
Figure 3 RNA cell line category: Cell line enriched (SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136750-GAD2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136750-GAD2
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- GAD65
- Antigen Species
- Human
- Peptide
- KGMAALPRLIAFTSEHSHFS
- Range
- 265-284
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
- Alternative Names
- GAD65
- Gene ID
- 2572
- UniProt ID
- Q05329
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GAD65"
Select a product category from the dropdown menu below to view related products.
Please select product type
MHC Tetramer Products for Other Applications
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-YF1466. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, Inhib, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
