What is the primary use of this MHC Tetramer in research?

This MHC Tetramer is primarily used for identifying and studying T cells specific to the Epstein-Barr virus (EBV). By using these tetramers, researchers can profile immune responses to viral infections, which is valuable in understanding immune mechanisms and T cell functions.

How does the MHC Tetramer facilitate flow cytometry analyses?

The MHC Tetramer, conjugated with PE, enhances flow cytometry by binding to antigen-specific T cells. This facilitates the detection and analysis of T cells with high specificity, aiding in detailed immune response studies.

PE-E*01:0303/EBV BZLF1 (SQAPLPCVL) MHC Tetramer (CAT#: MHC-CN0280)

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

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Datasheet
MSDS
COA

Datasheet

MSDS

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Lot Number

Specifications

Allele
E*01:0303

Class
Class I

MHC Species
Human

Antigen
BZLF1

Antigen Species
EBV

Peptide
SQAPLPCVL

Conjugate
PE

Application
FCM

Target

Antigen Introduction
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known viruses in the herpes family, and is one of the most common viruses in humans.

Alternative Names
EBV BZLF1; Epstein–Barr virus BZLF1

Gene ID
3783744

UniProt ID
P03206

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Mouse Antibody Products MHC Tetramer Products for Virology

CAT	Product Name	Application	Type
PABX-190	Recombinant Mouse Anti-ZEBRA Antibody (AZ130)	WB, ELISA, Neut, FuncS	IgG
PABX-190-S (P)	Recombinant Mouse Anti-ZEBRA Antibody scFv Fragment (AZ130)	WB, ELISA, Neut, FuncS	scFv
PABX-190-F (E)	Recombinant Mouse Anti-ZEBRA Antibody Fab Fragment (AZ130)	WB, ELISA, Neut, FuncS	Fab

CAT	Product Name	Application
MHC-CN0065	APC-B*35:01/EBV BZLF1 (EPLPQGQLTAY) MHC Tetramer	FCM
MHC-CN0066	PE-B*35:01/EBV BZLF1 (EPLPQGQLTAY) MHC Tetramer	FCM
MHC-CN0279	APC-E*01:0303/EBV BZLF1 (SQAPLPCVL) MHC Tetramer	FCM
MHC-YF347	B*35:01/EBV BZLF-1 (EPLPQGQLTAY) MHC Pentamer	FCM

Customer Reviews and Q&As

Customer Review Q&As

Great for Virology Research

This MHC Tetramer has significantly enhanced our virology research, especially concerning EBV. Its specificity for T cells has clarified many unknowns in antigen recognition, helping us map out immune responses with precision. The PE conjugation makes flow cytometry straightforward, delivering dependable results.

Effective Tool for T Cell Analysis

We've employed this tetramer for examining how well our models mimic T cell responses to EBV. The clarity it brings to our flow cytometry investigations, coupled with its specific targeting, makes it invaluable for in-depth virologic research.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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