Mouse Extrathymic Double-positive T Cell Makers (TCR, Cd3, Cd4, Cd8) Antibody Panel (VS-1225-YC80)
CAT#: VS-1225-YC80
The Extrathymic Double-positive T Cell Makers Antibody Panel is a set of 4 antibodies against mouse extrathymic Double-positive (DP) T cell makers (TCR, Cd3, Cd4, Cd8). This antibody panel facilitates the detection of extrathymic CD4⁺CD8⁺ double-positive T cells. It is suitable for investigating these rare T cell populations found in peripheral non-lymphoid tissues.
| Sub Cat | Component Name | Clone | Isotype | Target | Species Reactivity | Applications | |
| TAB-558CT | Hamster Anti-TCR Recombinant Antibody (clone H57) | H57 | Hamster IgG | TCR | Mouse | WB, FC | |
| FN-264CQ | Rat Anti-CD3E Recombinant Antibody (clone KT3) | KT3 | Rat IgG2a | CD3E | Mouse | FC, IHC | |
| VS3-XY322 | Rat Anti-Cd4 Recombinant Antibody (clone 4AGK1.5) | 4AGK1.5 | Rat IgG2b | Cd4 | Mouse | FC | |
| TAB-345LC | Anti-Mouse CD8A Recombinant Antibody (YTS169) | YTS169 | Mouse IgG | Cd8a | Mouse | FC |
Specifications
- Targets
- TCR, Cd3, Cd4, Cd8
- Research Area
- Mouse Extrathymic Double-positive (DP) T Cell
- Introduction
- While CD4⁺CD8⁺ cells are usually developing thymocytes, extrathymic DP cells can be found in the gut (IELs) or arise from CD4⁺ cells re-expressing CD8α (or vice versa) during inflammation. In the gut, they often represent a regulatory or highly activated effector phenotype tailored to the mucosal environment.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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