H-2Kb/Gallus gallus OVA (SIINFEKL) MHC Monomer
CAT#: MHC-YF199
This product is a MHC monomer of biotinylated peptide/MHC complex composed OVA-derived peptide of SIINFEKL sequence covering 257-264 and H-2Kb molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- OVA
- Antigen Species
- Gallus gallus
- Peptide
- SIINFEKL
- Range
- 257-264
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein.
- Alternative Names
- OVA; Ovalbumin
- Gene ID
- 396058
- UniProt ID
- P01012
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Versatile OVA MHC Monomer
We purchased this biotinylated H-2Kb monomer loaded with the SIINFEKL peptide for our custom tetramer assembly. The monomer quality is excellent, and it allowed us to create high-quality multimeric reagents for detecting OVA-specific T cells in our assays.
High Quality Ovalbumin Reagent
This monomer is a key component for our antigen-specific T cell analysis. The peptide loading is consistent, and the biotinylation allows for flexible use. It has performed reliably in our studies involving the model antigen Ovalbumin.
Q&As
-
Is this product a tetramer or a monomer?
A: This product is an MHC Monomer. It consists of a biotinylated peptide/MHC complex which can be used to generate tetramers or other multimeric reagents by the user, typically by adding fluorescently labeled streptavidin.
-
What is the specific peptide loaded onto this H-2Kb monomer?
A: The monomer is loaded with the classic OVA peptide sequence SIINFEKL (residues 257-264). This is a widely used epitope for studying CD8 T cell responses in C57BL/6 mice.
View the frequently asked questions answered by Creative Biolabs Support.
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