APC-H-2Ld/P1A (LPYLGWLVF) MHC Tetramer
CAT#: MHC-CN0187
Specifications
- Allele
- H-2Ld
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- P1A
- Peptide
- LPYLGWLVF
- Conjugate
- APC
- Application
- FCM
Target
- Alternative Names
- P1A
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High Sensitivity Detection
The tetramer's high sensitivity has allowed us to detect low-frequency P1A-specific T cells that we previously could not identify. This has been critical for our studies on early-stage tumor immunosurveillance. The quality of the results has greatly improved our experimental data and publications.
Great for Adoptive Transfer
We used this tetramer to track adoptively transferred P1A-specific T cells in our mouse models. It provided clear and reliable detection, allowing us to monitor T cell behavior in vivo effectively. This has been critical for our immunotherapy research.
Q&As
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Is this tetramer compatible with standard flow cytometry protocols?
A: Yes, the H-2Ld P1A MHC Tetramer is designed to be suitable for standard flow cytometry protocols. It is conjugated to APC, enabling multicolor staining and simultaneous analysis of multiple cellular markers alongside antigen-specific T cell detection.
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Can this tetramer be used to study autoimmune responses?
A: Yes, since P1A is a self-antigen, this tetramer can help in studying autoimmune T cell responses and mechanisms of self-tolerance. By detecting P1A-specific CD8+ T cells, researchers can investigate how the immune system discriminates between self and non-self and explore factors that lead to autoimmunity.
View the frequently asked questions answered by Creative Biolabs Support.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0188 | PE-H-2Ld/P1A (LPYLGWLVF) MHC Tetramer | FCM |
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