Recombinant Human Anti-CMV pp65 Soluble TCR (C25) (C-Cys)

CAT#: VS-0622-YF3043

Human TCR (C25) recognizes CMV pp65 peptide (NLVPMVATV) in the context of HLA-A2. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.

Specifications

  • Host Species
  • Human
  • Target
  • CMV pp65
  • Species Reactivity
  • CMV
  • Epitope
  • NLVPMVATV
  • MHC
  • HLA-A2
  • Clone
  • C25
  • Type
  • Soluble TCR (C-Cys)
  • Related Disease
  • Cytomegalovirus infection
  • TCR Expression Strategy
  • C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.

Target

  • Alternative Names
  • pp65; CMV; Cytomegalovirus
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Breast cancer biomarkers at key points during disease progression
Stable C25 Clone Format
The C-terminal Cys strategy used for this C25 clone provided a very stable reagent. We utilized it to recognize the CMV pp65 peptide NLVPMVATV in the context of HLA-A2, facilitating our research on the lower matrix phosphoprotein.
Breast cancer biomarkers at key points during disease progression
Essential For CD8+ Studies
We are studying the strong CD8+ T cell response to CMV, and this product was essential. It specifically targeted the major constituent of virion bodies, allowing us to collect precise data on antigen recognition and specificity.

Q&As

  1. What family of viruses does CMV belong to?

    A: Cytomegalovirus (CMV) is a member of the herpes virus group. This group includes herpes simplex virus types 1 and 2, Varicella Zoster Virus, and Epstein Barr virus. CMV is also known as human herpesvirus 5 (HHV-5).

  2. What format is the C25 clone provided in here?

    A: This specific product of the C25 clone is provided as a soluble TCR expressed with the C-terminal Cys strategy. The alpha and beta chains form a heterodimer based on the C-terminal Cysteine, containing variable and partial constant regions.

View the frequently asked questions answered by Creative Biolabs Support.

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