Abciximab
CAT#: TP-100CL
Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.



Specifications
- Type
- Biotech
- Trade name
- Reopro
- UNII
- X85G7936GV
Target
- Function
- Fab fragment of chimeric (human/mouse) mAb 7e3 that inhibits platelet aggregation by binding to the glycoprotein iib/iiia integrin receptor
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03.May,24
Q&As
-
Is there a recommended secondary antibody to pair with Abciximab?
A: The choice of secondary antibody depends on the primary antibody's species and isotype. Consult the datasheet or technical support to select a suitable secondary antibody.
-
How can I validate Abciximab's performance in my lab?
A: Validate performance by comparing expected results with known positive and negative controls, and performing replicate experiments to ensure consistency.
-
Can Abciximab be used with other antibodies in multiplex assays?
A: Yes, Abciximab can be combined with other antibodies in multiplex assays, given that cross-reactivity and compatibility are confirmed beforehand.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TP-100CL, RRID: AB_3112055)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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