Abciximab (CAT#: TP-100CL)
Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.
Specific Inquiry
ELISA
Figure 1 Anti-Human CD41 Recombinant Antibody (TP-100CL) in ELISA
ELISA analysis of TP-100CL was performed by coating with Human Integrin α2bβ3 (4 μg/mL). Abciximab TP-100CL were added with a series of dilutions (from 0 ng/mL to 5000 ng/mL). HRP-Rabbit Anti-Human IgG, F(ab')2 fragment antibody (1: 4000) were used to detect the bind Abciximab.
WB
Figure 2 Anti-Human CD41 Recombinant Antibody (TP-100CL) in WB
Western blot analysis of TP-100CL was performed by loading Human Integrin α2bβ3.
TP-100CL incubation concentration: 4 ng/μL.
The secondary antibody: HRP-Goat-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (2 μg)
Lane 2: Reducing antigen (4 μg)
DB
Figure 3 Anti-Human CD41 Recombinant Antibody (TP-100CL) in DB
Dot blot analysis of TP-100CL was performed by loading Human Integrin α2bβ3.
TP-100CL incubation concentration: 4 ng/μL.
The secondary antibody: HRP-Goat-Anti-Human IgG (H+L)
NC: Negative control
PC: Positive control
Specifications
- Type
- Biotech
- Trade name
- Reopro
- UNII
- X85G7936GV
Target
- Function
- Fab fragment of chimeric (human/mouse) mAb 7e3 that inhibits platelet aggregation by binding to the glycoprotein iib/iiia integrin receptor
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
Customer Reviews and Q&As
Customer Review
Q&As
-
Excellent Purity
The purity of Abciximab is impressive. It performed exceptionally well in our western blot assays, providing clear and specific bands. Highly recommended for research work. -
Noteworthy Specificity
The specificity of Abciximab is worth mentioning. It has provided highly specific detection in ELISA setups, reducing background noise significantly. -
Compatible with Multiple Methods
We've successfully used Abciximab in various assays including ELISA, DB and western blotting. It's compatible with multiple experimental setups.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TP-100CL, RRID: AB_3112055)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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