Abciximab

CAT#: TP-100CL

Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.

Tested Data
Figure 1 Anti-Human CD41 Recombinant Antibody (TP-100CL) in ELISA Figure 2 Anti-Human CD41 Recombinant Antibody (TP-100CL) in WB Figure 3 Anti-Human CD41 Recombinant Antibody (TP-100CL) in DB

Specifications

  • Type
  • Biotech
  • Trade name
  • Reopro
  • UNII
  • X85G7936GV

Target

  • Function
  • Fab fragment of chimeric (human/mouse) mAb 7e3 that inhibits platelet aggregation by binding to the glycoprotein iib/iiia integrin receptor
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Breast cancer biomarkers at key points during disease progression
Excellent Purity
The purity of Abciximab is impressive. It performed exceptionally well in our western blot assays, providing clear and specific bands. Highly recommended for research work.
Breast cancer biomarkers at key points during disease progression
Noteworthy Specificity
The specificity of Abciximab is worth mentioning. It has provided highly specific detection in ELISA setups, reducing background noise significantly.
Breast cancer biomarkers at key points during disease progression
Compatible with Multiple Methods
We've successfully used Abciximab in various assays including ELISA, DB and western blotting. It's compatible with multiple experimental setups.
Breast cancer biomarkers at key points during disease progression Ja**s
03.May,24
Suitable for WB
Western blot: Abciximab bound to α2bβ3 at 1/500 dilution. HRP-labeled goat anti-human Fab as a secondary antibody.

Q&As

  1. Is there a recommended secondary antibody to pair with Abciximab?

    A: The choice of secondary antibody depends on the primary antibody's species and isotype. Consult the datasheet or technical support to select a suitable secondary antibody.

  2. How can I validate Abciximab's performance in my lab?

    A: Validate performance by comparing expected results with known positive and negative controls, and performing replicate experiments to ensure consistency.

  3. Can Abciximab be used with other antibodies in multiplex assays?

    A: Yes, Abciximab can be combined with other antibodies in multiplex assays, given that cross-reactivity and compatibility are confirmed beforehand.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TP-100CL, RRID: AB_3112055)

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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