Recombinant Human Anti-KCNB1 Soluble TCR (SB3) (KIH) (CAT#: VS-0622-YF6695)
Human TCR (SB3) recognizes KCNB1 peptide (LLAILPYYV) in the context of HLA-DRB5. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Low expression in lymph node.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1979/166705_A_7_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1979/166705_A_7_8_val_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42434/166700_B_9_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42434/166700_B_9_5.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42434/166700_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42434/166700_A_7_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (ASC diff, CACO-2, HL-60, hTCEpi, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158445-KCNB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158445-KCNB1
Specifications
- Host Species
- Human
- Target
- KCNB1
- Species Reactivity
- Human
- Epitope
- LLAILPYYV
- MHC
- HLA-DRB5
- Clone
- SB3
- Type
- Soluble TCR (KIH)
- Related Disease
- Breast cancer
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0522-LC144 | Rat Anti-KCNB1 Recombinant Antibody (VS-0522-LC144) | IB, IP, IHC | Rat IgG2b |
| VS-0522-LC145 | Human Anti-KCNB1 Recombinant Antibody (VS-0522-LC145) | IB, IP, IHC | Human IgG1 |
| VS-0522-LC146 | Rabbit Anti-KCNB1 Recombinant Antibody (VS-0522-LC146) | IB, IP, IHC | Rabbit IgG |
| VS-0522-LC150 | Rat Anti-KCNB1 Recombinant Antibody (VS-0522-LC150) | IB, IP, IF | Rat IgG2b |
| VS-0522-LC151 | Human Anti-KCNB1 Recombinant Antibody (VS-0522-LC151) | IB, IP, IF | Human IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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