Recombinant Human Anti-NY-ESO-1 Soluble TCR (C-Cys) (VS-0622-YF2735) (CAT#: VS-0622-YF2735)
Human TCR recognizes NY-ESO-1 peptide (SLLMWITQV) in the context of HLA-A2. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in testis.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/ihc_selected.jpg
Figure 2 Low expression in endometrium 1.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_B_4_3_val_selected.jpg
Figure 3 Testis
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_A_6_6.jpg
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_A_6_6.jpg
Figure 4 RNA cell line category: Group enriched (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000268651-CTAG1A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000268651-CTAG1A
Specifications
- Host Species
- Human
- Target
- NY-ESO-1
- Epitope
- SLLMWITQV
- MHC
- HLA-A2
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Melanoma
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- CTAG1A; CT6.1; CTAG; Cancer/Testis Antigen 6.1; Cancer/Testis Antigen 1; Autoimmunogenic Cancer/Testis Antigen NY-ESO-1; CTAG1; LAGE2A
- Gene ID
- 246100
- UniProt ID
- P78358
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IgG Antibodies
MHC Tetramers for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3805z | Mouse Anti-CTAG1A Recombinant Antibody (clone 35B7) | WB, IP, IF, IHC | Mouse IgG1, κ |
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