Recombinant Human Anti-SNRPG Soluble TCR (WG4) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2388)
Human TCR (WG4) recognizes SNRPG peptide (IMLEALERV) in the context of HLA-A*02:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (WG4). Please note that the activity is not guaranteed.

(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/67814/1536_B12_1_selected.jpg

(Immunohistochemical staining of human rectum shows moderate nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/ihc_selected.jpg

(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_B_9_5.jpg

(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_A_9_3.jpg

(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_A_9_4.jpg

(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_A_9_5.jpg

(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_A_4_6.jpg

(Cells in basal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity: 75%-25% Cells in spinous layer Staining: High Intensity: Strong Quantity: 75%-25% Endothelial cells Staining: High Intensity: Strong Fibrohistiocytic cells Staining: High Intensity: Strong Langerhans cells Staining: High Intensity: Strong Quantity: 75%-25% Lymphocytes Staining: High Intensity: Strong Melanocytes Staining: High Intensity: Strong Quantity: 75%-25% Vascular mural cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_B_6_8.jpg

(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64152/143816_A_8_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143977-SNRPG
Specifications
- Host Species
- Human
- Target
- SNRPG
- Species Reactivity
- Human
- Epitope
- IMLEALERV
- MHC
- HLA-A*02:01
- Clone
- WG4
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Small Nuclear Ribonucleoprotein Polypeptide G; Sm Protein G; SnRNP-G; Sm-G; SMG; Small Nuclear Ribonucleoprotein G; PBSCG
- Gene ID
- 6637
- UniProt ID
- P62308
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1919 | PE-A*02:01/Human SNRPG (IMLEALERV) MHC Tetramer | FCM |
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