Human IgA1/A2m1-digesting Enzyme (Yielding Fab and Fc) (CAT#: VS-0724-CJ8)

Human IgA-digesting enzyme is an IgA-specific protease that digests human-IgA1 or IgA2m2 molecules at the site above the hinge, yielding Fab and Fc fragments. It is recommended to incubate the samples at 37 °C for 16-18 hours (pH 6-8) without reducing conditions. It can not digest human A2m2 or A2m3. This protease was cloned from E. ramosum and produced in E. coli with His-tag for easy purification.

Specific Inquiry
  • Datasheet
  • MSDS
  • COA

Specifications

  • Cleavage Site
  • Above the hinge: PCP | VPS (IgA1); PCP | VPP (IgA2m1)
  • Species Reactivity
  • Human
  • Specificity
  • Human IgA1, IgA2m1
  • Reaction Condition
  • Overnight reaction; Physiological buffers
  • Format
  • Lyophilized
  • Original Source
  • Erysipelatoclostridium ramosum

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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