Human IgG1-digesting Enzyme A (Yielding Fab and Fc) (CAT#: VS-0724-CJ3)
This product is a cysteine protease that digests human-IgG1 molecules at the site above the hinge, yielding Fab and Fc fragments. It is recommended to incubate the samples at 37 °C for 16-18 hours (pH 6-8) without reducing conditions. Human IgG1-degrading enzyme A was cloned from S. agalactiae and produced in E. coli with His-tag for easy purification.
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Specifications
- Cleavage Site
- Above the hinge: DKT | HTC
- Species Reactivity
- Human
- Specificity
- Human IgG1
- Reaction Condition
- Overnight reaction; Physiological buffers
- Format
- Lyophilized; Immobilized; Kit
- Original Source
- S. agalactiae
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For Research Use Only. Not For Clinical Use.
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