Insulin-mediated Glucose Uptake Pathway Antibody Panel (AKT1, GLUT4, IRS1)

CAT#: VS-0725-YC41

The Insulin-mediated Glucose Uptake Pathway Antibody Panel are sets of 5 antibodies, precisely engineered for the simultaneous detection of key proteins involved in insulin signaling and glucose transport. Our extensive set includes antibodies against phosphorylated AKT1 (pSer 124), phosphorylated AKT1 (pSer 473), GLUT4, and phosphorylated IRS1 (pSer 636). This panel provides a powerful and streamlined tool for investigating diabetes, obesity, and metabolic disorders, ensuring robust and reproducible results for your studies.

Sub Cat Component Name Clone Type Target Species Reactivity Applications  
VS3-WK519 Rabbit Anti-Phospho-AKT1 (S124) Recombinant Antibody (clone JJ08-46) JJ08-46 Rabbit IgG Phospho-AKT1 (S124) Human, Mouse, Rat WB, ICC, IHC
VS3-CJ871 Rabbit Anti-AKT1 (phospho S473) Recombinant Antibody (VS3-CJ871) Rabbit IgG AKT1 Human, Mouse WB, ICC, IF, IHC
VS3-CJ872 Rabbit Anti-AKT1 Recombinant Antibody (VS3-CJ872) Rabbit IgG AKT1 Human, Mouse, Rat WB, ICC, IF, IHC, IP, FC
FAMAB-1375CQ Mouse Anti-IRS1 Recombinant Antibody (clone IRS 8-63) IRS 8-63 Mouse IgG1 IRS1 Human, Mouse, Rat IB, IP, WB
VS-0725-YC223 Goat Anti-GLUT4 Polyclonal Antibody Goat IgG GLUT4 Human, Mouse, Rat IHC, WB
More Infomation

Specifications

  • Targets
  • AKT1 (pSer 124), AKT1 (pSer 473), GLUT4, IRS1 (pSer 636)
  • Species Reactivity
  • Human, Mouse
  • Research Area
  • Insulin-mediated glucose uptake pathway
  • Introduction
  • The insulin-mediated glucose uptake pathway is a critical signaling cascade that allows insulin, a hormone secreted by the pancreatic beta cells, to regulate blood glucose levels. Its primary function is to facilitate the rapid uptake of glucose from the bloodstream into insulin-sensitive tissues, predominantly skeletal muscle and adipose (fat) tissue, for either immediate energy use or storage. This pathway is fundamental to maintaining whole-body glucose homeostasis, and its dysregulation is a hallmark of insulin resistance and type 2 diabetes.
  • Storage
  • Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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