Recombinant Mouse Anti-ChgA Soluble TCR (BDC-10.1) (ZIP-Fos/ZIP-Jun)
CAT#: VS-0622-YF860
Mouse TCR (BDC-10.1) recognizes ChgA peptide (WSRMDQLAKELTAE) in the context of HLA-DQ8. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (BDC-10.1). Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17369/1734_B3_2_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23/250_A_8_3.jpg
Normal Tissue
Figure 3 Pancreas
Pancreatic endocrine cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17369/141310_A_3_3.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100604-CHGA
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Specifications
- Host Species
- Mouse
- Target
- ChgA
- Species Reactivity
- Mouse
- Epitope
- WSRMDQLAKELTAE
- MHC
- HLA-DQ8
- Clone
- BDC-10.1
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Lung malignancy
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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Datasheet
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COA
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